Trifluoromethylthiolating
WebJul 7, 2014 · A new, electrophilic trifluoromethylthiolating reagent, N-trifluoromethylthiosaccharin, was developed and can be synthesized in two steps from …
Trifluoromethylthiolating
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WebA transition-metal-free direct trifluoromethylthiolation of indole derivatives under mild conditions has been developed. Commercially available sodium trifluoromethanesulfinate … WebAug 25, 2014 · A new, electrophilic trifluoromethylthiosaccharin was developed and can be synthesized in two steps from saccharin within 30 minutes. A new, electrophilic trifluoromethylthiolating reagent, N-trifluoromethylthiosaccharin, was developed and can be synthesized in two steps from saccharin within 30 minutes. N …
WebApr 2, 2024 · Chinese Chemical Letters 2024年1期. Chinese Chemical Letters的其它文章 Diverse synthesis of the C ring fragment of bryostatins via Zn/Cu-promoted conjugate addition of α-hydroxy iodide with enone WebMar 3, 2015 · A simplified electrophilic trifluoromethylthiolating reagent 1c was then identified that can react with a wide range of nucleophiles such as Grignard reagents, arylboronic acids, alkynes, indoles, β-ketoesters, oxindoles, and sodium sulfinates under mild reaction conditions. A variety of functional groups were tolerated under these conditions.
WebMar 13, 2024 · We disclosed herein a straightforward strategy for the synthesis of unprecedented N-((trifluoromethyl)thio), N-(trifluoromethyl) amines using a combination of isothiocyanates with a fluoride source and an electrophilic trifluoromethylthiolation reagent.More interestingly, the scalability of the methodology has been demonstrated and … WebA boron-catalyzed direct α-trifluoromethylthiolation of carboxylic acids was developed. Catalytically generated boron enediolates reacts with electrophilic SCF3 reagent, N-SCF3-phthalimide, to provide α-SCF3 carboxylic acids without the need of substrate pre-activation. The method is applicable to direct modification of bioactive carboxylic ...
WebMar 30, 2016 · With regard to the high lipophilicity of the trifluoromethylthio group (CF 3 S–), there is a growing interest in the development of efficient methods for the incorporation …
WebMay 18, 2024 · In this review, special attention is given to the preparation of (hetero)aryl C–H bonds by Friedel–Crafts-type trifluoromethylthiolation and transition-metal-catalyzed … look over your shoulder o\u0027jaysWebJul 24, 2024 · A multicomponent catalytic reaction between ketones, Morita–Baylis–Hillman (MBH) carbonates and trifluoromethylthiolating agents is devised for straightforwardly … look palantir pack palantir affirm andurilWebThe first C−SCF 3 /SeCF 3 cross-coupling reactions using gold redox catalysis [(MeDalphos)AuCl], AgSCF 3 or Me 4 NSeCF 3, and organohalides as substrates are reported.The new methodology enables a one-stop shop synthesis of aryl/alkenyl/alkynyl trifluoromethylthio- and selenoethers with a broad substrate scope (>60 examples with up … hopvision heimkino beamerWebDodoneine (Ddn) is one of the active compounds identified from Agelanthus dodoneifolius, which is a medicinal plant used in African pharmacopeia and traditional medicine for the treatment of hypertension. In the context of a scientific program aiming at discovering new hypotensive agents through the original combination of natural product discovery and … look over your shoulder the o\\u0027jaysWebAug 15, 2024 · Electrophilicity parameters (E) of some popular trifluoromethylthiolating and difluoromethylthiolating reagents were determined by following the kinetics of their reactions with a series of ... look pantalon cargo hommeWebThis important transformation process has been applied in several elegant decarboxylative fluorinations. 8 Shen and co-workers described the silver-catalyzed oxidative decarboxylative trifluoromethylthiolation of alkyl carboxylic acids with electrophilic trifluoromethylthiolating reagent I in an aqueous emulsion . 8b Very recently, Glorius ... look over 和 look throughWebAs both trifluoromethylthio (CF3S) and trifluoromethoxy (CF3O) moieties have proved to be valuable functionalities in pharmaceutical chemistry, trifluoromethylthiolation and trifluoromethoxylation have received a great deal of attention. For the trifluoromethylthiolation reaction, a variety of efficient methods have been developed. … hopvision 1080p review