WebJul 21, 2024 · CTCF-mediated chromatin loops underlie the formation of topological associating domains and serve as the structural basis for transcriptional regulation. However, the formation mechanism of these loops remains unclear, and the genome-wide mapping of these loops is costly and difficult. Motivated by the recent studies on the … WebSep 7, 2024 · CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC.Scientists at St. Jude Children’s Research Hospital have found direct evidence that CTCF governs chromatin accessibility, the process of opening tightly spooled DNA so that genes can be expressed. The findings were …
Figure 4 CTCF deficiency-mediated HSC depletion has …
WebMar 11, 2024 · We quantitatively mapped CTCF occupancy genome-wide in primary human hematopoietic stem and progenitor cells (HSPCs), B cells, T cells, monocytes, and … WebNov 1, 2001 · Tel: +1 323 865 0816; Fax: +1 323 865 0102; Email: [email protected]. Open in new tab Download slide. Figure 1. (A) ... All CTCF-binding sites except the sixth were revealed to be hypermethylated. (B) The methylation status of individual molecules containing the sixth CTCF-binding site by bisulfite … meeting planners international conference
CTCF and cohesin regulate chromatin loop stability …
WebThese studies revealed gains of chromatin accessibility around CTCF binding sites during HSPC activation, as such we additionally performed Low-C to directly profile the 3D conformation of human cord-blood derived LT-HSC and Short-term hematopoietic stem cells (ST-HSC), as well as Hi-C , ATAC-Seq and CTCF ChIP-Seq upon the OCIAML-2 cell … WebAcronym. Definition. TTCF. Twin Towers Correctional Facility (Los Angeles, California) TTCF. Two-Time Correlation Function (engineering) TTCF. Truckee Tahoe Community … WebMar 19, 2024 · CTCF and BORIS cooperate with additional Testis-specific transcriptional regulators to regulate gene expression in developing male gametes. CCCTC-binding … meeting planners international charlotte